The nucleus basalis (Ch4) in the alcoholic Wernicke-Korsakoff syndrome: reduced cell number in both amnesic and non-amnesic patients
نویسندگان
چکیده
منابع مشابه
The nucleus basalis (Ch4) in the alcoholic Wernicke-Korsakoff syndrome: reduced cell number in both amnesic and non-amnesic patients.
BACKGROUND The cholinergic nucleus basalis (Ch4) is an exclusive site of neurofibrillary degeneration in alcoholic patients with Wernicke's encephalopathy. AIM To test the hypothesis that the loss of Ch4 neurons contributes to the memory disorder, Korsakoff's psychosis, commonly seen in Wernicke's encephalopathy. METHODS Magnocellular basal forebrain neurons were quantified in alcoholic pat...
متن کاملThe nucleus basalis (Ch4) in the alcoholic Wernicke-KorsakoV syndrome: reduced cell number in both amnesic and non-amnesic patients
Background—The cholinergic nucleus basalis (Ch4) is an exclusive site of neurofibrillary degeneration in alcoholic patients with Wernicke’s encephalopathy. Aim—To test the hypothesis that the loss of Ch4 neurons contributes to thememory disorder, KorsakoV’s psychosis, commonly seen in Wernicke’s encephalopathy. Methods—Magnocellular basal forebrain neurons were quantified in alcoholic patients ...
متن کاملWernicke-Korsakoff syndrome
Wernicke-Korsakoff syndrome is a manifestation of thiamine (vitamin B1) deficiency, usually secondary to alcohol abuse, although there other non-alcohol related causes, such as bariatric surgery, and extreme dietary restriction. The syndrome is a combined manifestation of the short-lived but acute Wernicke’s encephalopathy (WE), followed by chronic Korsakoff syndrome. It is generally accepted t...
متن کاملNeuroimaging of the Wernicke-Korsakoff syndrome.
AIM Presented is the neuroradiological signature of acute Wernicke's encephalopathy (WE), derived from different types of magnetic resonance imaging (MRI) sequences. WE results from thiamine depletion, and its most typical antecedent is chronic alcohol dependence. Brain regions observed with in vivo MRI affected in acute WE include the mammillary bodies, periaqueductal and periventricular gray ...
متن کاملWernicke-Korsakoff Syndrome in Primary Peritoneal Cancer
Wernicke encephalopathy is a disease that constitutes a medical emergency, but one that can be reversed with thiamine repletion if it is recognized early. Patients with cancer have a high risk of Wernicke encephalopathy because of malnutrition, the use of chemotherapeutic agents, and disease progression. Korsakoff syndrome can follow or accompany Wernicke encephalopathy. Although patients can r...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Journal of Neurology, Neurosurgery & Psychiatry
سال: 1997
ISSN: 0022-3050
DOI: 10.1136/jnnp.63.3.315